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| antifungal drugs list |
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Antifungal drugs list
List of Antifungal Medications
Allylamines
Azoles
Imidazoles
Triazoles
Polyenes
Echinocandins
Allylamine
Allylamines area unit artificial antifungals with activity against a broad vary of dermatophytes. Allylamines act via inhibition of the squalene epoxidase formation that blocks the synthesis of steroid alcohol.
Allylamines (except terbinafine) area unit used as topical treatments. Oral antifungal is extensively used for the treatment of onychomycosis (fungal infection of the nail). It acts at AN earlier stage by inhibiting the formation of squalene epoxide, a precursor of lanosterol. Oral antifungal is the 1st alternative for treating infections of fingernails and toenails.
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| Antifungal drugs list |
Azoles
Azoles (imidazole and triazole derivatives) area unit an outsized cluster of artificial antifungal agents. Azoles area unit primarily fungistatic, and have a comparatively broad antifungal spectrum. The azole antifungals have several drug-drug interactions thanks to their interference with hemoprotein P-450 enzymes.
Imidazoles area unit thought-about first-line agents for many dermatophyte infections. Topical formulations area unit wide used for the treatment of superficial plant infections and epithelial duct fungal infection. Imidazoles area unit terribly unhealthful once taken orally, so that they area unit out there solely as topical formulations.
Triazoles area unit typically used for bar and treatment of invasive plant infections and general zymosis.
Arylguanidines area unit an utterly different category of artificial antifungal medication.
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Antifungal drugs list |
Polyenes
The polyenes area unit present compounds with a vast antifungal spectrum. Polyenes act by binding to sterols within the plant plasma membrane, thereby intrusive with membrane integrity and inflicting leak of essential metabolites. Most polyenes area unit used locally, however endovenous antibiotic remains a crucial agent for the treatment of general plant infections. The danger of nephrotoxicity limits the utilization of antibiotic B.
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| Antifungal drugs list |
Echinocandins
Echinocandins area unit the foremost recently developed category of antifungals. Echinocandins area unit used chiefly for the treatment of severe, invasive fungus infections. Echinocandins area unit safer than different types of antifungals and have a broad spectrum, and synergistic result together medical care.  |
| Antifungal drugs list |
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